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S & T NEWS - MEDICINE & HEALTH

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1.Snake venom studies yield insights for development of therapies for heart disease and cancer (Thu, 29 Jul 2010 00:00:00 EDT)
(American Society for Biochemistry and Molecular Biology) Researchers seeking to learn more about stroke by studying how the body responds to toxins in snake venom are this week releasing new findings that they hope will aid in the development of therapies for heart disease and, surprisingly, cancer.
2.Story tips from the Department of Energy's Oak Ridge National Laboratory, August 2010 (Thu, 29 Jul 2010 00:00:00 EDT)
(DOE/Oak Ridge National Laboratory) The following are story tips from the Department of Energy's Oak Ridge National Laboratory for August 2010.
3.Mechanism uncovered behind Salmonella virulence and drug susceptibility (Thu, 29 Jul 2010 00:00:00 EDT)
(University of Washington) Researchers have discovered a novel mechanism in Salmonella that affects is virulence and its susceptibility to antibiotics. The mechanism changes the bacteria's production of proteins in a previously unheard of manner. It allows Salmonella to selectively change its levels of certain proteins to respond to inhospital conditions. Although the mechanism had not been recognized before, scientists found evidence of a similar mechanism in all five kingdoms of life. The mechanism appears to have been conserved throughout the course of evolution.
4.Resting brain activity associated with spontaneous fibromyalgia pain (Thu, 29 Jul 2010 00:00:00 EDT)
(Wiley-Blackwell) A recent study from researchers at Massachusetts General Hospital and University of Michigan provides the first direct evidence of linkage between elevated intrinsic (resting-state) brain connectivity and spontaneous pain intensity in patients with fibromyalgia. This research shows an interaction of multiple brain networks, offering greater understanding of how pain arises. Details of the study appear online and in the August issue of Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology.
5.TNF blockers may increase the risk of malignancy in children (Thu, 29 Jul 2010 00:00:00 EDT)
(Wiley-Blackwell) The Food and Drug Administration received reports of malignancies in children using tumor necrosis factor a (TNF) blockers, raising concerns of an associated risk and prompting an investigation. Researchers from the FDA set out to identify all reports of malignancy in children using infliximab, etanercept, and adalimumab and their report is published in the August issue of Arthritis & Rheumatism, a journal of the American College of Rheumatology.
6.AMP responds to Genetic Test Registry request for information (Thu, 29 Jul 2010 00:00:00 EDT)
(Association for Molecular Pathology) Today, the Association for Molecular Pathology submitted written comments in response to the Request for Information made by the National Institutes of Health for its Genetic Test Registry. AMP conducted a survey of its membership to formulate a comprehensive response to the RFI.
7.Memory's master switch (Thu, 29 Jul 2010 00:00:00 EDT)
(American Friends of Tel Aviv University) A new study led by Dr. Inna Slutsky of Tel Aviv University describes GABA (γ-Aminobutyric acid), a natural molecule that occurs in the brain, which could be the main factor in regulating how many new memories we can generate. The understanding of these mechanisms might lead to the development of new memory enhancers and new treatments for neurodegenerative diseases such as Alzheimer's.
8.Most youth hockey injuries caused by accidents, not checking, UB study shows (Thu, 29 Jul 2010 00:00:00 EDT)
(University at Buffalo) Hockey fans likely would assume that body-checking -- intentionally slamming an opponent against the boards -- causes the most injuries in youth ice hockey. But they would be wrong.
9.Behind the secrets of silk lie high-tech opportunities (Thu, 29 Jul 2010 00:00:00 EDT)
(Tufts University) Tougher than a bullet-proof vest yet synonymous with beauty and luxury, silks spun by worms and spiders are a masterpiece of nature whose properties have yet to be fully replicated in the laboratory. But scientists have begun to unravel the secrets of silk. Tufts biomedical engineers report that silk-based materials have been transformed from commodity textile to a growing web of high tech applications.
10.Plant compound resveratrol shown to suppresses inflammation, free radicals in humans (Thu, 29 Jul 2010 00:00:00 EDT)
(University at Buffalo) Resveratrol, a popular plant extract shown to prolong life in yeast and lower animals due to its anti-inflammatory and antioxidant properties, appears also to suppress inflammation in humans, based on results from the first prospective human trial of the extract conducted by University at Buffalo endocrinologists.
11.New pathway to Parkinson's and Alzheimer's diseases (Thu, 29 Jul 2010 00:00:00 EDT)
(Sanford-Burnham Medical Research Institute) Sanford-Burnham researchers uncover new clues about the cause of brain cell death in neurodegenerative disorders such as Parkinson's, Alzheimer's and Huntington's diseases.
12.CAKE offers way forward for climate change adaptation (Thu, 29 Jul 2010 00:00:00 EDT)
(Island Press) The new website Climate Adaptation Knowledge Exchange (CAKE) is a joint project of Island Press and EcoAdapt. CAKE is aimed at building a shared knowledge base for managing natural systems in the face of rapid climate change and an innovative community of practice. CAKE will support the changes that conservation has to make with the changing planet.
13.Male breast cancer in family leads to high perception of risk, low likelihood of genetic counseling (Thu, 29 Jul 2010 00:00:00 EDT)
(University of Louisville) People with a family history of male breast cancer perceive themselves to be at higher risk of developing the disease than do patients with a family history of female breast cancer; however those with male breast cancer in their families are less likely to know about or seek genetic testing than those with a family history of female breast cancer, according to a study led by researchers at the University of Louisville's James Graham Brown Cancer Center.
14.Nano's brightest coming to Rice (Thu, 29 Jul 2010 00:00:00 EDT)
(Rice University) Registration is open for Year of Nano events to be held Oct. 10-13 in honor of the 25th anniversary of the Nobel Prize-winning discovery of the carbon 60 molecule, the buckminsterfullerene, at Rice.
15.Carnegie Mellon researchers create fluorescent biosensor to aid in drug development (Thu, 29 Jul 2010 00:00:00 EDT)
(Carnegie Mellon University) Carnegie Mellon University has developed a new fluorescent biosensor that could aid in the development of an important class of drugs that target a crucial class of proteins called G protein-coupled receptors (GPCRs). GPCRs are popular drug targets because of the pivotal role they play in cells' communication circuits responsible for regulating functions critical to health, including circuits involved in heart and lung function, mood, cognition and memory, digestion and the inflammatory response.
16.Study finds respiratory symptoms more reliable indicator of H1N1, not fever alone (Thu, 29 Jul 2010 00:00:00 EDT)
(Elsevier Health Sciences) New research shows that individuals with mild H1N1 infection may go undetected using standard diagnostic criteria, according to a study in the August issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology. The study concludes that coughing or other respiratory symptoms are more accurate in determining influenza infection than presence of a fever.
17.Gender-bending fish on the rise in southern Alberta (Thu, 29 Jul 2010 00:00:00 EDT)
(University of Calgary) Chemicals present in two rivers in southern Alberta are likely the cause of the feminization of fish say researchers at the University of Calgary who have published results of their study in the journal Environmental Toxicology and Chemistry.
18.Researchers identify key enzyme in DNA repair pathway (Thu, 29 Jul 2010 00:00:00 EDT)
(University of Texas M. D. Anderson Cancer Center) Researchers have discovered an enzyme crucial to a type of DNA repair that also causes resistance to a class of cancer drugs most commonly used against ovarian cancer.
19.A new ground zero for prostate cancer (Thu, 29 Jul 2010 00:00:00 EDT)
(Howard Hughes Medical Institute) A type of prostate cell that has been largely ignored by cancer researchers can trigger malignant prostate cancer. The studies provide researchers with a new tool for exploring the genetic changes that lead to prostate cancer. The advance may help in developing new treatments for the disease, which causes some 32,000 deaths in the United States annually.
20.The evolution of melanoma diagnosis: 25 years beyond the ABCDs (Thu, 29 Jul 2010 00:00:00 EDT)
(American Cancer Society) Twenty-five years after publishing the mnemonic "ABCD" to facilitate the early diagnosis of melanoma, the group who came up with that moniker says early detection remains a key factor in lowering mortality from malignant melanoma.

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